C. diff Infection: An Urgent Threat
CLOSTRIDIOIDES DIFFICILE INFECTION DECLARED
AN URGENT PUBLIC HEALTH THREAT1
C. diff emerged as an important pathogen, following the introduction of broad-spectrum antibiotics2
An increase in severe cases of CDI was noted in Canada, the United States, and Europe, which was attributed to the emergence of epidemic types of C. difficile3
Hypervirulent NAP1/B1/027 strain emerges in North America and Europe4
Reported that CDI eclipsed methicillin-resistant Staphylococcus aureus (MRSA) as the leading hospital onset healthcare-facility-related infection5,6
CDC identified CDI as an URGENT PUBLIC HEALTH THREAT1,a
CDC = US Centers for Disease Control and Prevention.
aCDC defines urgent threats as those that may not be currently widespread but have the potential to become so and require urgent public health attention to identify infections and to limit transmission.1
References: 1. Centers for Disease Control and Prevention. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed March 31, 2021. 2. Kelly CP. Clin Microbiol Infect. 2012;18(suppl 6):21-27. 3. Smits WK, et al. Nat Rev Dis Primers 2016;2:16020. 4. Fatima R, Aziz M. Cureus. 2019;11(1):e3977. 5. Lessa FC, et al. N Engl J Med. 2015;372(9):825-834. 6. Miller BA, et al. Infect Control Hosp Epidemiol. 2011;32(4):387-390.